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1.
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14 p, 1.8 MB |
COPD : systemic proteomic profiles in frequent and infrequent exacerbators
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Enríquez-Rodríguez, Cesar Jessé (Hospital del Mar (Barcelona, Catalunya)) ;
Casadevall, Carme (Hospital del Mar (Barcelona, Catalunya)) ;
Faner, Rosa (Hospital Clínic i Provincial de Barcelona) ;
Castro-Costa, Ady (Hospital Universitario 12 de Octubre) ;
Pascual-Guàrdia, Sergi (Hospital del Mar (Barcelona, Catalunya)) ;
Seijó, Luis (Universidad Autónoma de Madrid) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Peces-Barba, Germán (Universidad Autónoma de Madrid) ;
Monsó, Eduard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Barreiro, Esther (Hospital del Mar (Barcelona, Catalunya)) ;
Cosio, Borja G (Universitat de les Illes Balears) ;
Garcia-Navarro, Àlvar Agustí (Hospital Clínic i Provincial de Barcelona) ;
Gea, Joaquim (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Some patients with COPD suffer frequent exacerbations (FE). We hypothesised that their systemic proteomic profile would be different from that of non-frequent exacerbators (NFE). The objective of the present study was to contrast the systemic proteomic profile in FE versus NFE. [...]
2024 -  10.1183/23120541.00004-2024
ERJ Open Research, Vol. 10 (march 2024)
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2.
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9 p, 526.0 KB |
Burden of refractory and unexplained chronic cough on patients' lives : a cohort study
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Puente, Luis (=)) ;
Dávila, Ignacio (Hospital Clínico Universitario (Salamanca)) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ;
Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
Sola, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Nieto, María Luisa (Hospital Arnau de Vilanova (València)) ;
González-Barcala, Francisco-Javier (Universidade de Santiago de Compostela) ;
Cea-Calvo, Luis (Medical Affairs) ;
Sánchez-Jareño, Marta (Medical Affairs) ;
Rivas-Pardinas, Cristina (Medical Affairs) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Chronic cough (cough lasting for ≥8 weeks) can lead to significant impairment in quality of life (QoL). Using patient-reported outcomes, this cohort study assessed the perceived impact of chronic cough on QoL and everyday life in patients from outpatient hospital clinics with refractory chronic cough (RCC) or unexplained chronic cough (UCC). [...]
2023 - 10.1183/23120541.00425-2023
ERJ Open Research, Vol. 9 (september 2023)
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3.
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13 p, 1.1 MB |
Long-term efficacy of dupilumab in severe asthma by baseline oral corticosteroid dose
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Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Rabe, Klaus F. (Observational and Pragmatic Research Institute) ;
Price, David (Universitair Ziekenhuis Gent) ;
Brusselle, Guy (National Jewish Health) ;
Wechsler, Michael E. (Regeneron Pharmaceuticals Inc.) ;
Xia, Changming (Sanofi) ;
Pandit-Abid, Nami (Sanofi) ;
Gall, Rebecca (Regeneron Pharmaceuticals Inc.) ;
Rowe, Paul J. (Sanofi) ;
Deniz, Yamo (Regeneron Pharmaceuticals Inc.) ;
Jacob-Nara, Juby A. (Sanofi) ;
Radwan, Amr (Regeneron Pharmaceuticals Inc.) ;
Universitat Autònoma de Barcelona
Dupilumab has been shown to improve clinical outcomes long term while reducing oral corticosteroid (OCS) dose in patients with severe OCS-dependent asthma. This post hoc analysis assesses the impact of OCS dose at baseline (≤10 or >10 mg·day −1) on long-term outcomes of dupilumab treatment. [...]
2023 - 10.1183/23120541.00056-2023
ERJ Open Research, Vol. 9 (november 2023)
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4.
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13 p, 1.7 MB |
Consensus goals and standards for specialist cough clinics : the NEUROCOUGH international Delphi study
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Song, Woo-Jung (University of Ulsan College of Medicine) ;
Dupont, Lieven (University Hospitals Leuven (Bèlgica)) ;
Birring, Surinder S. (King's College London) ;
Chung, Kian Fan (Imperial College London) ;
Dąbrowska, Marta (Medical University of Warsaw) ;
Dicpinigaitis, Peter (Albert Einstein College of Medicine and Montefiore Medical Center) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fontana, Giovanni (University of Florence) ;
Gibson, Peter G. (University of Newcastle) ;
Guilleminault, Laurent (Hôpital Larrey and Center for Pathophysiology Toulouse Purpan) ;
Hull, James H. (Royal Brompton Hospital (Londres)) ;
Idzko, Marco (Medical University of Vienna) ;
Kardos, Peter (Maingau Clinic of the Red Cross) ;
Kim, Hyun Jung (Korea University College of Medicine) ;
Lai, Kefang (Guangzhou Institute of Respiratory Health) ;
Lavorini, Federico (University of Florence) ;
Millqvist, Eva (University of Gothenburg) ;
Morice, Alyn H. (University of Hull) ;
Niimi, Akio (Nagoya City University) ;
Parker, Sean M. (North Tyneside General Hospital) ;
Satia, Imran (McMaster University (Canadà)) ;
Smith, Jaclyn A. (University of Manchester) ;
van den Berg, Jan Willem (Isala Hospital) ;
McGarvey, Lorcan P. (Queen's University Belfast) ;
Universitat Autònoma de Barcelona
Current guidelines on the management of chronic cough do not provide recommendations for the operation of specialist cough clinics. The objective of the present study was to develop expert consensus on goals and standard procedures for specialist cough clinics. [...]
2023 - 10.1183/23120541.00618-2023
ERJ Open Research, Vol. 9 (november 2023)
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5.
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10 p, 398.9 KB |
Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia
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Torres, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Niederman, Michael S. (Weill Cornell Medicine) ;
Chastre, Jean (Groupe Hospitalier Pitié-Salpêtrière) ;
Ewig, Santiago (Kliniken für Pneumologie und Infektiologie) ;
Fernandez-Vandellos, Patricia (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Hanberger, Hakan (Linköping University) ;
Kollef, Marin (Washington University School of Medicine) ;
Bassi, Gianluigi L. (Hospital Clínic i Provincial de Barcelona) ;
Luna, Carlos M. (Hospital de Clínicas "José de San Martin") ;
Martin-Loeches, Ignacio (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Paiva, J.Artur (University of Porto Medical School) ;
Read, Robert C. (NIHR Southampton Biomedical Research Centre. University Hospital Southampton) ;
Rigau, David (Institut d'Investigació Biomèdica Sant Pau) ;
Timsit, Jean François (Paris Diderot University and Bichat Hospital) ;
Welte, Tobias (Medizinische Hoschschule Hannover and German Center of Lung Research (DZL)) ;
Wunderink, Richard (Northwestern University Feinberg School of Medicine) ;
Universitat Autònoma de Barcelona
A summary of the evidence and recommendations made in the ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia http://ow. ly/S3zA30iZfLa.
2018 - 10.1183/23120541.00028-2018
ERJ Open Research, Vol. 4 Núm. 2 (january 2018) , p. 28-2018
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6.
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9 p, 484.0 KB |
Outcomes reported on the management of COPD exacerbations : A systematic survey of randomised controlled trials
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Mathioudakis, Alexander G. (Wythenshawe Hospital) ;
Moberg, Mia (Hvidovre University Hospital) ;
Janner, Julie (Hvidovre University Hospital) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Vestbo, Jørgen (Manchester University NHS Foundation Trust) ;
Universitat Autònoma de Barcelona
Randomised controlled trials (RCTs) evaluating the management of acute exacerbations of chronic obstructive pulmonary disease (COPD) report heterogeneous outcome measures, thus rendering their results incomparable, complicating their translation into clinical practice. [...]
2019 - 10.1183/23120541.00072-2019
ERJ Open Research, Vol. 5 Núm. 2 (january 2019) , p. 72-2019
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15 p, 739.8 KB |
Advances in diagnostic tools for respiratory tract infections : from tuberculosis to COVID-19 - changing paradigms?
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Stojanovic, Zoran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gonçalves-Carvalho, Filipe (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marín, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Latorre, Irene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lacoma, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Respiratory tract infections (RTIs) are one of the most common reasons for seeking healthcare, but are amongst the most challenging diseases in terms of clinical decision-making. Proper and timely diagnosis is critical in order to optimise management and prevent further emergence of antimicrobial resistance by misuse or overuse of antibiotics. [...]
2022 - 10.1183/23120541.00113-2022
ERJ Open Research, Vol. 8 (september 2022)
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8.
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11 p, 694.5 KB |
Gene expression profile of epithelial-mesenchymal transition in tumours of patients with nonsmall cell lung cancer : the influence of COPD
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Xia, Yingchen (Hospital del Mar (Barcelona, Catalunya)) ;
Zha, Jianhua (Hospital del Mar (Barcelona, Catalunya)) ;
Curull Serrano, Víctor (Hospital del Mar (Barcelona, Catalunya)) ;
Sánchez-Font, Albert (Hospital del Mar (Barcelona, Catalunya)) ;
Guitart, Maria (Hospital del Mar (Barcelona, Catalunya)) ;
Rodríguez-Fuster, Alberto (Hospital del Mar (Barcelona, Catalunya)) ;
Aguiló Espases, Rafael (Hospital del Mar (Barcelona, Catalunya)) ;
Barreiro, Esther (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Epithelial-mesenchymal transition (EMT) is involved in the pathophysiology of lung cancer (LC) and COPD, and the latter is an important risk factor for LC. We hypothesised that the EMT gene expression profile and signalling cascade may differ in LC patients with COPD from those with no respiratory diseases. [...]
2022 - 10.1183/23120541.00105-2022
ERJ Open Research, Vol. 8 (july 2022)
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9.
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13 p, 1.6 MB |
Diffuse alveolar haemorrhage in children : an international multicentre study
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Ring, Astrid Madsen (University of Copenhagen) ;
Schwerk, Nicolaus (German Center for Lung Research (DZL)) ;
Kiper, Nural (Hacettepe University Faculty of Medicine) ;
Aslan, Ayse Tana (Gazi University Faculty of Medicine) ;
Aurora, Paul (Great Ormond Street Hospital for Children (Londres)) ;
Ayats-Vidal, Roser (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Azevedo, Ines (Universidade do Porto and Serviço de Pediatria) ;
Bandeira, Teresa (Centro Hospitalar Universitário Lisboa Norte) ;
Carlens, Julia (German Center for Lung Research (DZL)) ;
Castillo-Corullón, Silvia (Hospital Clínic Universitari (València)) ;
Cobanoglu, Nazan (Ankara University Faculty of Medicine) ;
Elnazir, Basil (CHI at Tallaght University Hospital (Dublin)) ;
Emiralioglu, Nagehan (Hacettepe University Faculty of Medicine) ;
Eyuboglu, Tugba Sismanlar (Gazi University Faculty of Medicine) ;
Fayon, Michael (CHU Bordeaux) ;
Gursoy, Tugba Ramaslı (Gazi University Faculty of Medicine) ;
Hogg, Claire (Royal Brompton Hospital (Londres)) ;
Kötz, Karsten (University of Gothenburg) ;
Karadag, Bülent (Marmara University Faculty of Medicine (Turquía)) ;
Látalová, Vendula (University Hospital Olomouc (Olomouc, República Txeca)) ;
Krenke, Katarzyna (Medical University of Warsaw) ;
Lange, Joanna (Medical University of Warsaw) ;
Manali, Effrosyni D. (Athens Medical School) ;
Osona, Borja (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Papiris, Spyros (2nd National and Kapodistrian University of Athens) ;
Proesmann, Marijke (KUL UZ Gasthuisberg) ;
Reix, Philippe (Université de Lyon) ;
Roditis, Lea (Children's University Hospital (França)) ;
Rubak, Sune (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Rumman, Nisreen (Makassed Hospital) ;
Snijders, Deborah (Università degli Studi di Padova) ;
Stehling, Florian (University Hospital Essen (Alemanya)) ;
Weiss, Laurence (Strasbourg University) ;
Yalcın, Ebru (Hacettepe University Faculty of Medicine) ;
Zirek, Fazilcan (Ankara University Faculty of Medicine) ;
Bush, Andrew (Imperial College London and Paediatric Respiratory Medicine) ;
Clement, Annick (Sorbonne Université) ;
Griese, Matthias (University of Copenhagen) ;
Buchvald, Frederik Fouirnaies (University of Copenhagen) ;
Nathan, Nadia ;
Nielsen, Kim G ;
Universitat Autònoma de Barcelona
Paediatric diffuse alveolar haemorrhage (DAH) is a rare heterogeneous condition with limited knowledge on clinical presentation, treatment and outcome. A retrospective, descriptive multicentre follow-up study initiated from the European network for translational research in children's and adult interstitial lung disease (Cost Action CA16125) and chILD-EU CRC (the European Research Collaboration for Children's Interstitial Lung Disease). [...]
2023 - 10.1183/23120541.00733-2022
ERJ Open Research, Vol. 9 (april 2023)
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10.
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11 p, 735.0 KB |
Unravelling young COPD and pre-COPD in the general population
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Cosio, Borja G (Universitat de les Illes Balears) ;
Casanova, Ciro (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Soler-Cataluña, Juan José (Hospital Arnau de Vilanova-Lliria) ;
Soriano, Joan B.. (Hospital Universitario de la Princesa (Madrid)) ;
García-Rio, Francisco (Hospital Universitario La Paz (Madrid)) ;
de Lucas, Pilar (Hospital General Universitario Gregorio Marañón) ;
Alfageme, Inmaculada (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Rodríguez González-Moro, José Miguel (Universidad de Alcalá) ;
Sánchez Herrero, María Guadalupe (GSK (Madrid)) ;
Ancochea, Julio (Hospital Universitario de la Princesa (Madrid)) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Chronic obstructive pulmonary disease (COPD) is commonly diagnosed when the airflow limitation is well established and symptomatic. We aimed to identify individuals at risk of developing COPD according to the concept of pre-COPD and compare their clinical characteristics with 1) those who have developed the disease at a young age, and 2) the overall population with and without COPD. [...]
2023 - 10.1183/23120541.00334-2022
ERJ Open Research, Vol. 9 (february 2023)
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